PredniSONE side effects

My husband entered the hospital in Nov of 2005 for a surgery. He almost died in the recovery room and from there things went from bad to worse. They put him on a massive dosage of Prednisone. 95 days later we were able to come home. About 2 weeks later he started vomiting and lost all energy. We returned to the hospital and the diagnosis came down as acute adrenal insufficency. He was pumped full of Prednisone again. From there he went to a very slow wean and he got completely off the drug. No problems. This year he suffered a fall resulting in extreme trauma and blood loss. Back to the hospital where it was determined that his adrenals were again in crisis. Got him all mended and on the way out the door when a nurse decided that he should have a pneumovax. Within 24 hours we were back in the hospital with my husband in critical condition with three life threatening situations. His kidneys were shutting down, his blood pressure was beyond the danger zone (low) and he had cellulitis. Back home again to another slow wean. We are down to 5mg now and are hopeful at the next appointment to be able to start weaning further and back to zero. We were given Dexamethasone Sodium Phosphate for injection in case of any trauma in the future. In addition, my husband now wears a MediAlert bracelet which notes his condition and that in case of accident/trauma Dexamethasone Sodium Phosphate is to be given. Anyone on steroids should register with MediAlert at 1-800-854-1166.

What everyone needs to know is that the adrenals are responsible for a person's feeling of well being. When you are on a steroid, you need to wean very, very slowly to let your adrenals start doing the job on their own. The reason Prednisone is often prescribed is that it comes in as low of a dosage as 1mg and can be split 4 ways for 1/4th mg per dosage. For those that cannot tolerate Prednisone, Hydrocortisone is available. 10 mg of Hydrocortisone is the same as 2.5 mg of Prednisone. Hydrocortisone can also be split.

Interesting earlier post about hearing pulse in ear.
I heard my blood squirting through my veins in/around my ear yesterday.
Didn't start prednisone until today. Figure that one out?

I was diagnosed with ulcerative colitis in 2003, have been treated with Asacol ever since, and was in remission for nearly 5 years. I flared in December of 2007, and had my first experience with prednisone; I was on 40 mg/day for nearly 6 months. I gained 35 pounds, got the moon face, double-chin, tummy fat, muscle aches, extreme mood swings, excruciating headaches, night sweats, and UNCONTROLLABLE hunger. I, too, noticed the sensitive teeth, and now I feel like my enamel is really thin...almost see-through. Anyway, I've been off prednisone for about 5 months. The moon face went away for the most part, but my cheeks still seem a little chubbier than before, and my double-chin is a lot smaller, but still there. I've lost about half the weight, but only after joining weight watchers and working out 6 days a week. I feel like I can't lose any more weight to save my life. Does anyone have any suggestions? I never struggled with weight prior to taking this stupid drug. I'd appreciate any input.

I am writing on behalf of my elderly parent, Carmela, who has been diagnosed with Lupus since 1991. She has been on a small dose of prednisone since her diagnosis in 1991. In the last several months she has developed very many odd hazey type grey spots all over her body. Dermatologists and doctors are not giving her any answers. They took her off predisone because they THINK this may be the cause. She is on an inhaler and does not like it. She wants to go back on the prednisone as she is feeling chest congestion and lethargy. I read an article on the internet that describes prednisone may cause unusual bruising. I'm not sure if this is what her spots are. They are only the color grey and appear to be beneath the skins surface. They are soft or hazy looking. They are small, about the size of a dime. Has anyone heard of this before in Lupus (prednisone) patience. Any info you have is sure appreciated. S. ******

So far i am a 14 year old boy facing prednisone and have been on this drug over 4+ month periods at 10 mg first time and 100 second time. I have chrons's disease and it is hard to treat when it has a flare, so they have to put me on prednisone. I have experienced some of the worst side effects imaginable along with many other suffering victims of this drug, and they include: Headache, Severe Acne, Flu-Like Symptoms, High Blood Pressure, 50+ Pounds Gained, Moon face, Stomach Pains, and Much More. After i have been weened completely off i have notice these: SCARY Heart Palpitations, Out of Breathe, Feels like something is beating in my stomach, and feels like my heart drops to my stomach like pacing.

I had RSD (Reflex Sympathetic Dystropy in my (R) ankle which was only relieve by 5 nerve blocks. Does taking Prednisone bring back this condition?
I am on Prednisone for a month and have started to experience some sharp pains in my (R) ankle moving from inner aspect to middle then back to inner aspect.

I was admitted through the ER in sept. i had previously taken Bactrim for a bug bite on my foot three months prior. I had been severely bruising and had some lab work done. I got a call from my Dr. around midnight to go to ER immediately. My platelet count was at 11,000 a normal being 100,000-400,000. I went to ER and was admitted for 5 days. After running test after test there was no conclusion to what had caused this low platelet count but I was diagnosed with ITP. From here they put me on 50 mg/day of Prednisone for 1 month. I have now started to taper 40/ 2 weeks. 30/2 weeks. But then the side- effects started to come so fast. At first it was just sweating, minor anxiety, mood swings, and slight increase of appetite. Now that I had tapered my adrenal gland is suppressed much more and I am going through withdrawal. I am 21 years old I am 5'7" and I weighed 118 two weeks ago, since I have gained 12lbs of water weight. I am working out daily and eating healthy, although it is more than I used to eat. I have some family friends that work at Stanford University and they are ITP specialists. They told me their regimen for Prednisone is a 5mg/wk taper instead of 10/ 2 weeks. So the past two weeks I have been going down by 5. Today was my second day at 20 mg. I have gone through all of the mentioned side- effects except the back hump. I am hoping and praying that these symptoms will clear asap. And to everyone else out there your not alone.

I have been on Prednisolone about 4 times in recent years. the highest dose was last year when i was on 80mg reducing weekly by 5mg. I have had most of the side affects you all talk about above. I have severe colitis so the side-effects of this drug are something i have to put up with. at the moment i have all the classic side-effects i usually get, rapid hunger, swelling to my face (moon face), neck has layer of fat, swollen back (buffalo hump), bruising easily, horrible taste in my mouth, swollen stomach. the one good side effect is it gives me lovely smooth skin lol. anyway the point of my post isn't to rip this drug appart as i have to say for me its a wonder drug and this time has prevented me from having my bowel removed! from personal experience once you finish the steroid treatment after a few weeks you'll notice the swelling go, my hunger usually fizzles out quite quickly (altho i have a large appetite in the first place!!) none of the side effects are permanent, so please all rest assured you will go back to normal just try not to put on too much weight while on the drug.

Started with a Pred pak for a sinus infection. Made my heart race and had tach and early heartbeat, which kept me from sleeping. Went to Cardiologist. Several doctors denied that the Pred would cause the rapid heartbeat. Then the Cardiologist did an echo and found a pericardial effusion and some weird spots on my lungs. They suspected lung cancer which may cause the effusion, so I had surgery to do a pericardial window and a lung biopsy. Then a pulmonologist decided to put me on Pred again...steady dosage...because she didn't know what else to do. (Didn't have lung cancer) I didn't have any more funny heartbeats, so maybe the pred didn't cause it after all. But I've gained 40 pounds. My hair has grown faster, and I've gotten some facial hair (not supposed to have that, being a female)...which I call fur. Moon face with cheeks that are hard, muscle cramps, can't sleep, but once I do go to sleep, I can't wake up. Tired all the time, headaches, joint pain-sometimes severe, dry skin, generally bad attitude, with very little patience, low potassium levels which add to my muscle cramping problems, difficulty swallowing, indigestion which I've never had, with painful and burning reflux. And occasionally when I eat, I have the rapid heartbeat again. I go in search of food like I'm going to store it in my thighs for winter. Anything you eat will turn to fat, including protein. Can't wait to get off this stuff which will take until June of next year. Then my doctor says it will be 3 months before all these effects wear off. No one told me I would get fur.

My son 35yrs old was given Prednisone for an allergic reaction. He has a history of Bi-polar disorder. His family doctor prescribed this. He went into total psychosis , destroyed his own home, and is now sitting in jail on charges of Criminal Mischief.....When is someone going to put a black box warning on this drug?

i have been on prednisone for 5 years off and on and he moon face is there the hair loss the weight i really want to come off it so bad the asthma is a big issue in my life i wish they would come out with a better drug for us asthma patients the withdrawals i have been going through are the hair loss i use to have long thick beautiful hair thin face smaller body i am hoping some day i will get it all back
hopeful

Extreme Weakness, extreme excessive sweating, nausea, dizziness, itching, terrible headaches.In addition, I seemed to have contacted a moderate case of the flu. At least I had what seemed like the flu. However it is possible that it was just more of the same from the prednisone. My doctor gave me prednisone for a pinched nerve in my neck and a herniated disk in the same #7vertebrea. He gave me 12 days. As soon as I started taking it, I began to feel very weak, I had headaches, terrible exploding headaches. I found that I began to itch on my arm for no apparent reason, except for a bracelet in the area.In addition, I began to have excessive sweating, extreme sweating, the water would be pouring down my face. At that time, I would feel my heart pounding have some dizziness, and just overall bad feeling. It was debilitating, I spent a lot of time on the couch because I could not function in my daily activities. I went from exercising for 90 minutes to barely being able to get through 15 minutes. My question is will I go back to "normal" when this medicine gets out of my system. What is the half life of this drug? Should I do a detox of some sort. Worst of all, the problem with my neck has not really resolved and I will probably need some other sort of intervention. I never got that burst of energy that other people experienced with this medication.

I have experienced, avascular necrosis of both hips (resulting in total hip replacements) and avn of both solder (this time it resulted in partial shoulder replacements) Not to mention as everyone else has the thin skin, the weight gain. I have been on prednisone for 8 years - it is part of my immune suppressant cocktail that I take everyday. I have been on 4mg for approximately 5 years. It's very hard to lose the extra weight, the moon face lessens after a time but it is hard to tell because of the weight gain.

What side effects should one expect who has been prescribed 1000mg (one thousand) oral Prednisone.

Ok here's my story with Prednisone. Let me first give you a little back ground info on me. Born with a VSD, that was repaired at 8 months of age, only after developing severe pneumonia. Was fine as a child growing up until at 18 i developed asthma. i am 29 now and have been on and off prednisone during that time. During that time however I have always been on a metered dosage pack that has always tapered usually within 5 days with no side effects.

Now lets talk present day with me. First off I went in back in early Sept. for what I thought was just a sinus infection, turns out my lungs were so tight, i was immediately put on 80 mg for 5 days straight, and you guessed it no tapering. Those 5 days were the worst five days of my life. I have SVT- taychcardia and the med made it worst, I was running around like I was on Speed or something. Also, I had started to urinate like crazy. Headaches, nausea, muscle pain as well as joint pain. i can not walk without feeling as though my knees, and ankles are going to break. Also, i am not as foccused as I usually am. Ever since that faithfully day in September I have been on this stuff. it has already been 2 months and im on 40mg now. And I cannot sleep at all at night and during the day now i crash once it seems like the prednisone starts wearing off. its horrible. I am going to go see the Pulmanologist Monday hopefully he will have some answers, and Im dreading him telling me i may have COPD, from a protien defiency(sorry for spelling, this med is messing with my thought process). Any who, i cant just stop taking it, i have been warned about that. something has to give or my body may give up.

hope this helps.

this med is good if used correctly but i agree Doctors need to fully warn patients before hand of all possible side effects.

Crohn's Disease. I took 80 - 100 mg of this double-edged sword of a drug for over a year. I never noticed the side-effects (moon face, mood swings, permanent fat tissue swelling). I was so very ill from the Crohn's that nothing else existed.

Prednisone worked wonders in the short term, but trying to get off of it was an entirely different story. This drug plays an integral role in the body and touches critical systems and weaning off of it is awful. In the past 10 years, it seems that doctors are more careful about prescribing it, but too often I think people find themselves on the other side of it and seeing how the long-term effects and side-effects have severe impacts on their life.

If you haven't started taking prednisone, make sure you read and research it before you do. It took me at least a year to get used to living without it, and I needed surgery to remove the fat-tissue under my eyes because it was so swollen.

I had a chronic sinus infection and my doctor put me on Levaguin and 80 mg of prednisone. I am 62 and I take only synthroid as a prescribe. drug. I told my doctor I was a borderline diabetic. She told me the side effect were bone weakening in the hip and pelvis and stomach upset. At first I had a lot of energy and sleep a lot less. I just thought I was getting better. I tapered down to 1 1/2 . After taking them for 11 days I was not able to function. My body was under extreme distress, I have very excellent blood pressure and I am in very good health. I have been off the drug for 4 days. I am still experiencing sweating, hypertension, extreme muscle spasms. I am unable to wear my contacts, I am short tempered and I am normally the opposite. I have horrible headaches and I very seldom ever get headaches. I told my doc and she said it would go away in time.
My body is fatigued I am have trouble focusing,sleeplessness. I don't know where to turn at this point. Sometimes I feel like I should go to er because of the hyperventilating and rapid heart beat. I am afraid to exercise. I am eating a lot of high protein foods, I am not gaining weight, I have lost 7 lbs in two weeks. PLEASE EVALUATE THE RISKS OF THIS DRUG IT HAS BEEN A NIGHTMARE FOR ME. DOCTORS DON'T ALWAYS TELL YOU THE WHOLE TRUTH AND THEY NEED TO BE HELD ACCOUNTABLE FOR THIS.

My name is M. and I recently and FINALLY got off of prednisone. I was on it for 7 years and came to believe that I could never get off it, until I was finally referred to an endocrinologist, who helped me to get off of it. Unfortunately, my adrenal gland has stopped working so.... I now take a medication with virtually no side effects called hydrocortisone. I will probably have to take it for the rest of my life, but its a BILLION TIMES BETTER than the horrifying prednisone.
-TO L. IN AUSTRALIA- I hope this tid bit of info can be helpful to you. I don't know if you've seen an endocrinologist or know that if you're disease can be managed by another med you can probably go from the pred to the hydrocortisone. I truly hope the best for you, You are only the second person I've ever found who's been on the pred for longer then I was. I hope I've been of some help to you truly, my heart goes out to you.

Hi everyone.
I was prescribed prednisone for a hand injury that the swelling would not go down. I took it for 4 weeks. In the end of the first week I started breaking out in a rash that itched like crazy. They were small bumps that had nothing in them and they itched so bad I scratched them raw in my sleep. I informed the doctor about the rash and he told me it was to late in the game to get any side effects. This medicine also caused me to become very irate from any little thing. It also made me to lose my job while under a workers comp doctors care. This was about 6 years ago and I still am battling the rashes. They come and go but when they are apparent they take a long time to go away. I used to heal very fast but now it takes forever for an injury to heal. I have had blood work done and even had my liver checked out. They say I am as healthy as a horse so to speak. The rashes have scarred me all over. The bumps would turn to sores that took about 6 months to heal and they hurt, burned and itched all the time. I tried everything to control the itch and pain. I finally mixed aspirin with alcohol and some lotion together and this helped enough to get a fairly good night sleep as I was becoming exhausted. I am learning to deal with it in time but I will never be the same. My thinking is far from my normal thinking.
I had a list of side effects from prednisone and it was four pages long and the very first one was, Instant Death! The only side effect I was told by the doctor was that I might become easily irritated. In my opinion I think all doctors should give you an option after he has presented you with ALL the side effects of a prescribed drug and let you be the judge if you should take it or not. I now have a different doctor and he has prednisone as a drug I can not take. This medicine might be good for some people but it can have life changing effects for those that can not take it.
I feel for anyone that has had bad effects from it and hope you get over it some day.

Started taking 20 mg prednisone today for a bout of inflammation in my jaw and ear. I felt great when I first took the pill but now 7 hours later I am having terrible aches and pains in my hips, legs and shoulders. I am trying not to think that everything that can go wrong will go wrong but I feel worse than the ear ache I started with. Has anyone experienced such quick aches?

hya everyone,my partner has been on prednisone for over 6months while having chemotherapy 4 bone cancer.He is being weaned off the drug slowly and is now on half dose and is experiencing very bad joint pain,headaches,sweating along with depression and lower back pain.Hopefully after coming off the drug completely these symptoms will eventually go away.We sympathize with all who has to go through similar situations.

Hi there, Was on Prednisone for a sinus problem for a month 40mg down to 5mg and then off. Straight away got terrible aches and pains and stomach swelled out with lots of gas. Got scopes done all clear now the stomach pains have gone, got this flu hazzy brain feeling and aches. Could this be the Prednisone been off it now 7 weeks?

Hello everyone, I just started taking Prednisone today for severe Sciatica. I have read all your stories and now im so weary of taking another pill. Some of the side effects that y'all have experienced are awful. I think i would go crazy if i got all of that. I am on the Medrol Dose Pack and i started 2 pills before breakfast and now i have some stomach pains. Its sad that you have to take this for pain and inflammation and then end up with all other kinds of problems. Thanks for sharing your stories. I think im gonna stop taking it all together. Stacey

Hi everyone well yesterday i started to to take Prednisone 2 hour later my heart is racing along with high blood pressure , so ill try to calm my self down blood pressure kind off got back to normal but heart still beating rapid, today i woke up my blood pressure was fine but my heart still pounding do ya know how long it t takes for my heart to go back to normal , and im sorry to hear about everybodys different reactions to this stupid pill hope everybody gets better.

I agree that this drug is of evil. My mother was treated for 3 years on and off long term use for Wegener's Disease. She just tapered off her last dose, the docs are telling her she is done with it, thank the good Lord. She has told her doctor of all of her symptoms, manic episodes, severe depression, hallucinations and just recently the doctor suggested that it "may" be steroid psychosis. My mother inquired if there was some meds that could help b/c over time, it just seemed to get worse. She told her that she wasn't getting enough prednisone to cause this. Wasn't getting enough...when she was first diagnosed, she was given 3000 mg b/c she was near death, after that, each follow-up consisted of 40 plus mg, and I am talking 2 to 3 month stretches...but she wasn't getting enough to cause steroid psychosis??? My mother came to me one day and asked me not to leave my 3 year old daughter with her alone ever and of course I asked why. She told me that she had thoughts of harming those around her, that they would actually play out in her head. Through my tears, I asked my mother if she followed through with these thoughts, would that give her some relief, and she replied yes. At this point, I know it is bad. I have found a site that lists treatments for steroid psychosis and plan on not stopping until a physician agrees to help us. My prayers are with everyone that is experiencing these horrible drug interactions and side effects.

I have Autoimmune Hemolytic Anemia (AIHA), was diagnosed in Feb. 2008. Have been ill for several years and finally it came to a head in Feb. I had a blood transfusion and then in the hospital 6 days later with a hgb of 4.0. I was so toxic and my blood so screwed up I nearly died. I was given another transfusion then (total of 5 pints of packed red blood cells) and started on Prednisone. For 3 days given liquid Pred injections, starting at 1000mg, tapering down to 250mg., then on the pill form at 100mg. Sweat poured off of me dosing down. I was off work for 2 months. I am still tapering but am now at 1mg. DR. added another drug, Danazol, after getting to about 10mg because my blood started going crazy again. My side affects with Prednisone have been, Euphoria, no depression, LOTS of hyper brain activity, thoughts running a 100 miles an hour but body at slow speed.Visual problems and a feeling of being highly drugged. 2 to 3 hours of sleep each night, compulsive behaviors and a lot of pacing back and forth. Couldn't hold my concentration because my mind wandered so much. Extreme Tremors in my back, hands and head. Wanted to talk constantly, if no one was around I talked to my Chihuahua or the TV. My cheeks puffed up and became hard and had a fat pocket puffed up on left side of my neck. My dog thought I was crazy, she was tired of the lights being on at 3 or 4 in the morning. Legs looked skinny but didn't gain weight until I got to about 60mg. Gained 25 lbs total. Tapering caused bad spasms in my calves, feet and hands. Thigh muscles would get extremely weak each time I went down a dose. At 50mg I started getting sleepy and could hardly stay awake. Went back to work at 35mg and couldn't remember how to sign on to my computer. Some memory problems since I was in the hospital, couldn't remember how to spell words I knew as a young girl. Started having hip pain about 3 months into the Pred, that hasn't stopped. At 10mg feet, knees, shoulders hurt deep in the sockets, muscles below my neck knot up, may take a while to totally get off this. Read on a couple of blogs where people cut a 1mg tab into 4 pieces to taper off the Pred. because of side effects. Had thrush in the beginning and break outs of shingles. I hope to God I never have to get back on this drug again, it is so HARD on the body but it did do what it was given for, to repress my immune systems. My next step is Spleen surgery, hope this is a cure for me, am sick and tired of being sick and tired. Wouldn't advise anyone to take Pred unless it's a life or death situation. It's prescribed too liberally and people have multiple problems, worse than I have experienced. I've probably forgotten some things, but there's enough I've mentioned to give you an Idea it's not good, but if Pred is all you have then you do what you gotta do!! My puffy cheeks have went down though, now my hair has become curly but at least I have hair and my chihuahua stills loves me!!!

i have been an asthmatic since the age of 2 years old i am now 24 years old. preds as i call it has been a part of my life since then. i have a number of reactions to it from gaining 30 lbs in les than 6 months to almost definitely hallucinating. i urinate frequently,my hubby says that i'm a leaking tap. i cry and grumble at times for no reason: yes mood swings like rain in spring time. i even threw away my wallet after a dose of preds three months ago. i laugh uncontrollably. i get depressed. sleep for long hours one time and then become insomniac for days. i am super hyper. i am creative and expressive and get even better for a few hours after taking preds. also i appear to have an attention disorder at times. i have acute hearing i.e i hear like a fox really well and then some day si behave like an 89 year old with a hearing aid. i get rashes on allergic reactions to things i've been using all my life like band-aid.i don't like it in fact when the doctor gives me 8 to be taken 3 times daily for a week, i take two and feel better without all the side effects. i am so fat its a shame. i was tall and lean and sexy now i am tall heavy and my hubby still says sexy. we all hate it don't we?!

Started taking prednisone about 3 months ago for a serious flare-up of my Sciatica. My Sciatica was so bad that I couldn’t even stand up. After a couple days of prednisone, I was able to walk, but still had pain on my left side, from my back down to the tip of my big toe. Symptoms started getting better, but then the side effects started. Gain 40 lbs, can’t sleep, muscles are so weak it’s hard to walk, blurred vision… one day (laying on my bed) I noticed I couldn’t even see the clock on the cable box anymore. Lumps started appearing. One on my wrist and one big one on my upper arm. I cut my finger 5 days ago and it still hasn’t closed up completely yet. It even still bleeds. I know on the side of my pill bottle it says “This medicine may lower your ability to fight off infections”, but man! It sucks when you have a little cut that just won’t heal. Anyway, I’m sick of the side effects and they only seem to be getting worse. I’m stopping today! I would rather fight through the pain of my Sciatica than to deal with all these side effects. I just hope (and pray) that the side effects go away without doing (if not already) major damage.

After reading previous postings, my experience seems so minor. I was on prednisone for about 2 weeks, starting at 50mg per day for 5 days, then 40mg for 2 days, 30 mg for 2 days, 20 mg for 2 days, then 10 mg for 2 days. I was put on it for severe poison ivy. I experienced sleeplessness, irritability, very quick to be irrationally angry and also had drastic changes in my triglyceride levels. I was hungry all the time, and extremely restless. 3 weeks before starting treatment my triglyceride level was 108, and cholesterol was 205. 5 days after treatment ended, my triglyceride level was 216, and cholesterol 214, all after being on a completely Vegan diet the whole time. It's my understanding that prednisone makes your body be in a state of alert while taking this drug, juicing you up to complete fight or flight status 24/7 while on it. Even 7 days later after being off of it, my patience is still limited. I will never take this stuff again.

Hello everyone! I just want to thank each and every one of you for your postings. On more than one occasion I would come to this site because without all of you I probably would have truly lost my mind. I just want to give a brief history of what's been going on with me because if it can help one other person then it's all worth it. In 2005, I go vaccinated for chickenpox, I work in health care, never had them, and wanted to start having children since I'm 36. A month after the vaccine I broke out in a horrific rash ALL OVER and had it until April of 2008. I went to the hospital where I had the vaccine, 5 dermatologists, 3 Infectious Disease, various medical doctors and no one knew what it was. This April, I was admitted to the hospital with Autoimmune Hemolytic Anemia. After 3 hematologists, the last one feels the vaccine threw my immune system into a tizzy. I started with 60mg of Prednisone and eventually got down to 2.5mg. The hemolysis(body produces antibodies that attacks it own body) started again so I went to a new Hematologist and was put back up to 30mg and just got put down to 10mg today. Right now my biggest concern is the hair loss. I use to have such thick hair and now I cry almost daily because I loose so much. I am going to try the Ensure like someone posted just to see if that helps. I drink protein shakes, take Silica, multivitamins (Solgar) that have biotin, and going to try Nioxin shampoo. I have terrible mood swings and now I feel like I am going through withdrawal. It's almost like I want to take more just to feel better. I know that sounds crazy. The big fat moon face, my joints feel like they pop out, confused easily, can't sleep, and just can't really leave my house and live a normal life since April. I HATE IT!!! The only thing that helps me feel better when the daily prednisone "kicks in" is walking and exercising. I feel so bad for everyone this drug is just awful. I get angry because not one person told me what life was going to be like on prednisone. I think that is just mean. That's why these postings are so important. I know this is entirely to long but I feel so much better getting my story out there. Did everyone's hair eventually grow back. I don't know if I will have any left next month. Thank you all so much.
GG

My 15 year old son was put on prednisone for orbital pseudo tumor about 5 weeks ago.He hasn't had many side effects except vomiting and the pattern seems to be every other day he has tapered down from 40 mg. to 20 mg. I thought maybe the pseudo tumor might be causing vertigo , i don't know if vertigo is sporadic like this? The vomiting didn't begin until right before his next day reduction on his prednisone. I don't know what to think of this drug at this point ,it did make his eye which was swollen completely shut, begin opening up about 5 hours after his initial dose of 40mg.But i don't know why he is vomiting off and on and it didn't completely stop his eye from hurting. Now the doctors want to biopsy his eye muscle since he is not responding well to prednisone reduction.God be with you all who are struggling with this medicine.

Hi All,

I was diagnosed with dermatologists when I was 14 years old and put on very high dosage of prednisone to get my disease under control (40 mg a day at the beginning). My muscle enzymes were out of control (CPK was almost 8,500 when it should be less than 215) and I was barely mobile, huge amounts of weight loss, alopecia, Raynaud's, etc. That was 11 years ago and I am now almost 100% better. Prednisone saved my life, but the side-effects were TERRIBLE! Especially for a girl going through puberty. Kids at school don't understand you're sick, and they can be extremely cruel. Luckily for me a large number of my family members are in the medical profession all over the world and my parents were able to pool knowledge to find the best treatment for me without all the horrible side effects. An uncle in Germany suggested I take a Prednisone alternative widely available in Europe called Diflazacort. This medicine is not available in the states apparently because the FDA thought it was exactly like Prednisone so was unnecessary. I'm sure this is some pharmaceutical company lobbying to preserve Prednisone's monopoly on inflammatory diseases, but regardless it makes finding Diflazacort difficult for Americans. This is a HUGE shame since this medicine gave me ALL of the benefits of Prednisone with NONE of the side effects. My mood swings, water retention, increased appetite, hazy brain, thinning skin, etc etc etc ALL stopped with Diflazacort. This wasn't only true for me either. A family friend had been diagnosed with Crohn's at the time and he was put on Diflazacort from the beginning of his treatment after seeing how I reacted to it and NEVER had any of the negative side effects I had to deal with. Really this drug was like a miracle for me. Prednisone prevented my sure death, but Diflazacort gave me my life back in its entirety. I've now been off of any steroid for 7 years and my muscles are fully back to normal. Some of the fat deposits Predinose caused still linger, but to most people's eyes I'm totally back to normal. I wish I could find everyone having problems with Prednisone side-effects and tell them about Diflazacort. Even though it isn't available in the states (although I heard recently they are trying to get it approved again since a number of studies showed Diflazacort is much more effective treating Crohn's than Prednisone is) you can get it on the internet or if you have doctor friends abroad as I did. I'm always wary of buying drugs over the internet since there's no control so I would suggest contacting doctors in Europe or Asia directly or through your doctor here in the states. Anyways, I wanted everyone to know that some people do get better and I wish you all the best of luck!

Hi All,

I was diagnosed with dermatologists when I was 14 years old and put on very high dosage of prednisone to get my disease under control (40 mg a day at the beginning). My muscle enzymes were out of control (CPK was almost 8,500 when it should be s no control so I would suggest contacting doctors in Europe or Asia directly or through your doctor here in the states. Anyways, I wanted everyone to know that some people do get better and I wish you all the best of luck!

I was put on PredniSONE for my asthma. On day two of taking it I started to feel really awful. I couldn't lay down, sit down or stand without feeling like I was going to explode. So hubby took me to emergency. My blood pressure was sky high. 201 over 90, they put me on a fluid retention iv drip. I had retained way to much fluid and it made my blood pressure go skyhigh.

I have asthma and have been prescribed prednisone several times for it. Every time i take it i break out in an awful acne looking rash all over my arms and my chest and sometimes even my face. it doesn't start until about 3 days after i have started the medicine and it doesn't go away for about 2 weeks and it itches the whole time. I told my doctors that every time they would try to prescribe it and they did not believe me they said no one could be allergic to prednisone but it has happened to me 6 times now and it has never happened before i had prednisone or on many other medicine since then.i finally got them to switch the steroid to a different kind but every kind seems to do it. i had to refuse steroids the last time i was in the hospital for my asthma they just would not accept that i could not take the medicine.

eat avocados to help with cramps. No one tells u that prednisone depletes potassium. Better avocados than banana because prednisone also raises your blood sugar.

I have two experiences with Prednisone to share: I am a 52 year old woman, married, no kids. One year ago I came down with a serious case of shingles on the top and inside of my left eyelid. What started out as a bump that looked like a pimple or a bite on a Friday afternoon (and I don't have acne), spread across and under my eyelid by Mon, morning, up into my eyebrow and down the side of my nose. My eye felt like there was glass in it every time I blinked. I got to the doctor on Mon, the dermatologist on Tues and the opthamologist on Wed. All confirmed shingles. I have never felt anything to excruciating in my life! The dermatologist prescribed a 3-week descending dose of Pred starting with 6 pills a day. I was also given Gabapentin (a nerve blocked), Acyclovir, a muscle relaxant, pain medication and two separate eye drops, one of which was also low-dose Pred. After the 3 week course of treatment was done, I had to continue for another week, but with lower doses.
Side effects: I did not notice any side effects except that my appetite was seriously jacked up! I ate anything and everything -- and then some! Food was my best friend and I hogged everything in site! In hindsight, when I try to assess myself and any changed, I guess I do have some attitude issues in that I am quicker to anger, quicker to react and respond and seem to "snap" a lot quicker.... Oh yeah I am also on antidepressants.... I now have one droopy eyelid due to the nerve damage from the Shingles and permanent damage to the cornea and tear ducts.... However I am not really sure how much of that is due to the Shingles and how much is due to the Prednisone.

My 89-year old mother was hospitalized in August for emphysema and chronic lung disease, she was down to 81 lbs. They treated & released her and she was on a descending dose of Prednisone for a week. She needed to gain some weight & gained 3 lbs! This was very good.... She is still smoking and her doctor will NOT insist she quit (I think they have given up). They put her back on a 2-week course of Pred again last week. Her appetite is back up Yeah! but she has some serious attitude and anger issues. We are only 1 week into the 2 weeks and I don't know how our family is going to stand taking care of this evil old woman during this Prednisone treatment, and afterwards. I'm sorry I ever let the doctor put her back on it--- however she is gaining weight and getting (falsely) stronger, which she needed.

I was prescribed the 4mg methylprednisolone pack along with 50 mg tramadol for acute tendinitis in my wrist. I took the first 3 days of the prednisone and only 2 doses of the tramadol over the three days. For a total of 60 mg of prednisone.

The first day I had hot flashes and insomnia but attributed it to the tramadol because I had never taken it before and had taken the prednisone several years ago for poison ivy with no adverse reactions. I didn't take the tramadol the second night and then took it again last night along with my daily dose of prednisone. I had extreme difficulty falling asleep, heart burn, hot flashes; and tossed and turned all night trying to fall asleep. At around 2am, I began to have difficulty breathing, tightening in my chest, confusion, and racing thoughts. It felt as though my throat was closing up on me. My anxiety progressed to the point that I was pacing back and forth. I woke my husband up and told him to prepare to take me to the ER. After calling my insurance's 24 hour help line, it was recommended that I go to the ER. I had an x-ray, blood work, urine drug screen, and echocardiogram. Luckily, everything was negative. The ER doctor told me that I likely had a reaction to the prednisone and commented that some people will experience these symptoms when taking it. He stated that he had a similar reaction when he took it and it felt like he was climbing the walls, which is an accurate description of my experience that night. He recommended that I either stop taking it altogether or call my primary care provider and cut it down. He prescribed me xanax and administered some to me at the ER which greatly helped. The next day I stopped taking the pred but am still having dizziness, chest tightness, hot flashes, and mental dullness. I have decided to never take this medication again. Fortunately, I don't have any of the physical sx that some have experienced, and my heart goes out to you. I think the mental symptoms were traumatic enough for me and can't imagine having both as I would be a basket case. I have mood swings, some melancholia, and am very fatigued.

I think it is imperative to research any medication that is prescribed to you before you take it. Many providers will say that side effects are rare, but my experience is that side effects are more common than rare. My prayers go out to those of you who are going through what I am going through. I hope that it clears our systems quickly because this is no way to live. I'd rather put up with the pain of tendinitis or carpel tunnel than to have these symptoms.

My daughter, 21yo, took prednisone off/on for 4 months, both oral and IV form, with the highest dose of 90mg over a two week period. The risk of bone death (Osteonecrosis, aka Avascular Necrosis) is not disclosed as a risk and 7,000 people a year get this from steroids! They gloss it over under the guise of "bone pain" or "bone fracture" near the osteoporosis risk so you think that by taking calcium and vit D supplements you're protected. What's really going on here is that the steroids cause the bone to die so if you have pain, PLEASE INSIST on an MRI because a regular x-ray will not show ON until it's in the advanced stages..and then you'll most certainly need joint replacement.
I'm not making light of the weight gain, or loss of hair or any of the myriad of other side effects that come with this drug, but when you're told that the joints in your body are dead...and that they'll eventually become brittle and break and cause so much pain it is often compared to bone cancer, then you'll really want to sue someone. But, I've tried that...it doesn't work. Because the drug is FDA approved...the manufacturer can't be held liable.

My daughter has ON in her right shoulder, both elbows, both wrists, both knees, and both ankles. She's considered "collateral damage" by the medical/legal communities because Prednisone is the "gold standard." This disease is a slow progressing disease which is often found as late as 10 years after stopping the steroid treatment. If you find it early enough, some surgical options exist to prevent the collapse of your bones, so if you have joint pain...PLEASE investigate with an MRI

Earlier this summer, I developed a case of shingles. It went away, but about a week ago a similar rash broke out. I thought that it was a second bout of shingles, but my doctor assured me that it would be impossible to contract the disease on different parts of my body. Because I am not home with my ordinary doctor, I had to see another doctor, who was unsure of what the rash could be, but nevertheless prescribed with with 50mg of Prednisone daily. I took my first dose today, and am reluctant to continue. I don't want to be a victim of any of the side effects, but am unsure as to whether there is another way to go about getting rid of the rash. Any advice that could be given so as to not have to continue with the Prednisone would be great. I don't want the rapid weight gain, depression, mood swings, etc.

My friend's mom who was in great health took this stuff and got osteoporosis and diabetes, became depressed, and then she died.

My 12 year old son has been on 60 mg of Prednisone for two weeks now. His side effects have not been bad at all up to this point. He's gained about 6 pounds. His brain is unusually active right after taking the drug, and this effects lasts a few hours. He's always been a wildly creative kid but prednisone seems to intensify is creativity and the productivity of his brain. He has Tourette Syndrome and his tics waned overnight after beginning the meds so that is a big bonus if prednisone is responsible for that. He has always been an insomniac since he was a baby but prednisone makes him sleepy, so sleepy he takes naps during the day and goes to bed early, sleeping soundly all night, so soundly he had an accident and wet his bed last night. His head sweats when he sleeps. He has infrequent periods of mild irritability. His appetite has increased but not unnaturally so. Seems like he finally has a sustained healthy appetite. He goes to 45 mg for two weeks tomorrow so I'm interested to see what new side effects this brings on. No stomach problems despite taking this along with very high doses of antibiotic. Maybe the prevacid he takes with Lactobacillus is helping with that and the fact that he takes his meds with small meals or lots of fluid.

what did anyone use as an alternative???....my daughter is currently having a severe wasp reaction, has been told to take prednisone, and I don't want to give it to her.

I have Crohns and had a flare up so I'm back on 40mg of Prednisone. I've been on 40mg now for 3 weeks and I start to tapper off in another 3 weeks. Well every time I start the prednisone again I get new side effects. This time, my gum are bleeding all the time and the pain in my knees are horrible! I still get the regular side effects, ie: Mood swings, joint pain, sleeplessness, sweating, swelling of my legs and hands, wanting to eat everything under the sun, moon face and my hair falls out! I wish the drug manufactures could develop a drug that would not be so hard on our bodies. I have to struggle with the pros and cons with every flare up. Do I want the weight gain, mood swings and hair loss or do I want to look good and be very sick! I'm 37 and was 16 when I found out I had Crohns.

Reading some of the other side effects (after posting my most recent side effects) has made me think back a long time to when I was about 10 or so, and my asthma had been acting up- I was given a sort-of high dose of prednisone. For about two-six months after taking it, I had really severe knee pain, sometimes where I couldn't even walk around the grocery store. Eventually, it went away, and I distinctly remember my mom asking my doctor a few years later if it could be the cause (too high a dose and no weaning off), and the doctor said it was possible. Sometimes, I will have general knee pain for no specific reason, but luckily it doesn't happen very often.

Once I came back to Buffalo to school and had taken my first allergy shot, my asthma flared up majorly, so my doctor put me on 10mg prednisone for 8 days, while at the same time putting me on Symbicort (and also at the same time, I have been taking 75mg Doxycycline for my skin issue), and it caused me to get thrush, even though I was rinsing my mouth after symbicort. I was given the impression by the P.A. I saw that taking Prednisone increases your chances of getting thrush. Has anybody else ever experienced this?

I am 49 yr old male and was diagnosed with a severe upper respiratory infection. Was put on Prednisone for 20 days. I never did experience depression, but I did experience the hyper state and was full of energy big time. It was actually nice ...had felt better than I had in a long time. Two of the side effects that I have been experiencing is sweating a lot more than normal ... I mean just the littlest of exercise and my shirt is soaked. Also my back and the back of my neck has broken out with acne ... that really hurts. I am using Desoximetasone which is a prescription cream and it has almost cleared all my acne up. I was about 250lbs and lost to 235lbs in the twenty days I was on it. I never changed my eating habits ...weight just fell off ...... man I wish they could put that it another pill without all the side effects. Now that I have been off for a couple of weeks ...I have gained some of the weight back ... but I'm really trying to change my eating habits and get back to 235 and go lower.
I wonder if everyone posting would also put their blood type on their comments. There are so many different opinions of Prednisone ...there has to be a reason why you have so many effects for some and very little for others. I did research this drug while I ws taking it and read that if you take it for longer than 30 days that your body will stop making the natural prednisone that it makes. Thats why you hear when people take it for long periods of time ...you are destined to take for the rest of your life.
As far as lung condition, I can breathe again and I think I'm totally cured ... I have a follow up with my lung doctor next week.
My prayers are with you guys .... I agree .. I don't think I want to take Prednisone ever again. My blood type is AB+

Hi I am a 44 year old asthma patient. I have had asthma since the age 2 and have been on & off prednisone since that time. As a child until age 20 I was on predinsone daily. My question is has anyone experienced nerve problems due to long time use? I do have muscle weakness and spasms, but I am interested in if anyone has had nerve problems. Please email me at ****** and refer to prednisone.

How interesting to find this site! I, too, was diagnosed with temporal arteritis on February 29 (no more leap years for me!). Because I was already blind in one eye (had no idea) and losing sight in the other eye, I was put on 100 mg daily of prednisone. I had no idea of what I was in for. Since that time I have been able to taper down to 42.5 mg daily, but I don't think I've missed a single side effect. Horrific headaches. A 25-pound weight gain so rapidly it was unbelievable, moon face like I've never seen, was thrown into diabetes right away. My blood pressure went haywire, my cholesterol went haywire (had never had problems with either of them). I think I agree that the most debilitating has been the muscle weakness and leg cramps. I have no balance, have had 3 serious falls. The latest is my skin is breaking down and I'm losing my hair. What hair I have is like somebody held a match to it and frizzed it. I'm short of breath, keep trying to exercise and it's like climbing a high-altitude mountain. Swelling of my feet to where I can wear NO shoes except for Crocs in about three sizes bigger than I ever wore in my life. Now I have a liver problem, am being sent to an "ultra-specialist" for this. The good news is that my remaining eyesight has been stable, and I am very thankful for that. I have been assured by multiple specialists that I would have been blind by now if not for the prednisone. Although it is very difficult for me to read by the time night arrives, and that was my chief "hobby." The other part of this whole sad saga (ha) is how much money my husband and I have been out this year -- unbelievable. Lab tests or doctors every single week and sometimes every single day. I am now under the care of 5 different specialists (ophthalmology, rheumatology, cardiology, hepatology and internal medicine), and it has been so incredibly expensive. This is even with fairly decent insurance. I have been told that I have at least six more months to go on this treatment, and then possibly another year on methotrexate. Thank God I have NOT experienced the depression that seems to be a common thread here. I am trusting in Him to get me through this itme and to come out on the other side completely cured. But it does get difficult in the meantime.

I took prednisone for 6 days ( the pack). Six the first day and five the next till day six I had one pill left. I have never experienced hair loss like this. I have a patch of hair that fell out in a circle the size of a 50 cent piece. I didn't notice it really falling out but noticed a bald spot and I freak out. I came on line to get info about this medication. This drug was ordered for me because I have severe pain in my back due to osteoarthritis, sciatica and back surgery. I was told taking this would help with the inflammation and might relieve some of the pain symptoms. Well, I think the pain would be better then the side effects that I suffer. I had loss of appetite and acne on my face. I feel dizzy and bloated. I pee all the time and seems like i visit the bathroom much more often for other reasons too. I have felt like a crazy lady and have less patience than normal. I hope that this does not last for ever. This is a small amount of the medication. I am sorry for those of you that have experienced a long period of time on this medication. I pray for you that they will find another alternative with less effects to your bodys.