Doxycycline Hyclate and tiredness

Hi there,
I took this medication for a supposed sinus infection, which after taking Azithromycin and than Doxy I have been really sick! I guess I had the flu and I panicked (because I am prone to sinus infections) and went on antibiotics without knowing for sure- after bloodwork and an x-ray there is no infection... so... after taking Doxy for 10 days I have been very exhausted-but mostly, flu like and muscle aches, its on day three after taking the last dose so I hope these muscle aches and tiredness goes away soon. I have noticed in the past that i get the same symptoms, like with Biaxin, and Cipro is really brutal... not to mention that I am allergic to Penicillin and Sulpha... so much fun lol

I was on Doxy for a month and a half due to mild acne. For the first month, I felt fine, however when I went to refill, things became awful. Although I did not notice the nausea or tiredness (because I took it before going to bed), I began to feel episodes of dizziness, confusion, inability to concentrate, and anxiety. I continued taking it because I had not been informed that these might be side effects. Eventually I had 2 panic attacks where my legs shook uncontrollably, I felt I could not breath, became really cold and sweaty, had racing thoughts that I might die, and felt incredibly confused. The attacks really scared me to the point where I was afraid of having another one. When I went to the doctor, they ran blood tests, told me everything was alright, diagnosed me with panic disorder, and gave me medication. Even though I told them I was taking this medication, no one ever told me this might be side effects. I have never had any mental problems and am an upbeat, happy person. While taking this, I had severe anxiety and bouts of depression where I felt like crying for no reason. I was afraid to be alone, I was afraid to workout, and afraid to leave the house. I could not study and thought my entire life was spinning out of control. I've been off it for 2 days and am feeling much better. Anxiety has decreased and depressive episodes are also decreasing. There should be better research on these drugs to inform consumers!

I have to take Doxy for 2 weeks twice a day. I have all the same side effects as everyone has listed here... very down and depressed, itchy pimple rash all over legs, face, neck, chest and back of shoulders, cold sores, severe headache, bloating, stomach pain, tiredness, lack of interest in anything, dry mouth, tingling toes and anxiety. Can't wait to finish the course, but am disappointed to read that the side effects carry on after stopping, does anyone know how long it takes for them to subside?

I have been taking 100mg Doxy twice a day for a week now. I'm really glad I found this site because I have been exhausted and I couldn't figure out why. I now know it must be the Doxy. I am taking it for an acne infection. I had been on birth control pills plus spironolactone for over two years- the combination of those two things had totally cleared my skin- so I foolishly decided to go off the birth control and spironolactone thinking my skin would be fine... well two months later my face started breaking out and by the third month I had severe cystic acne on my previously flawless skin! SO the dermatologist put me back on birth control pills and spironolactone, but since that would take at least a month to start working, he also prescribed the Doxy to clear up the infection faster. (I'm providing all of these details in case anyone else is taking Doxy for acne) so I started the Doxy and I think it was by the 4th day or so that I started feeling really tired. I've taken a nap every day for the past few days, AND slept all night. I was going to the gym daily but I could only do half my time on the treadmill last time I went and I haven't gone in two days. I'm also depressed- two days ago I cried three times that one day, yesterday I cried once. I'm just feeling sorry for myself etc- depression for no reason whatsoever. I had been feeling really good about myself all last month- going to the gym, feeling happy & high form the exercise endorphins, finally losing weight, etc, so I know there is NO reason for this tiredness and depression now other than the doxy. Just thought I'd share this because reading all of these posts has really helped me to see that it is just the drug. I will try very hard to force myself to go the gym, even if I can only do half as much. Also, my skin is SLOWLY getting better, but still have another week to go I think. The dermatologist said to take doxy for a month, but I will plan to stop as soon as my skin is clear- hopefully just one more week or two at the most. When my skin is clear I'll take it for one or two more days just to make sure the infection gets totally knocked out, but then that's it, so hopefully I can take it at least one week less than prescribed.

About feeling sick and the sore throat/ "stuck in throat" feeling- I cant stress enough to take it with lots of water and food, standing up, and don't lie down! First of all about feeling sick- I thought I was going to throw up for HOURS one time when I didn't take it with food- horrible feeling!! But this is even worse- about 15 years ago I took doxy and had to go to the hospital because I couldn't breathe, couldn't swallow, and had a splitting migraine headache etc... it had gotten stuck in my esophagus and took days for the symptoms to subside. It took the doctors forever to figure out it was the doxy. You would think I'd never take it again after that, but I know the throat symptom happened from taking it with very little water right before I lay down to go to bed, because I remembered doing that- and I woke up the next day with all of those problems. I still get a little bit of a feeling that I can't swallow as well as I normally can, but it's not that bad- sort of like when you are trying not to cry and feeling "choked up" or with "a lump in your throat"- that kind of a feeling. I think others have described this too, and it's unfortunately normal, to an extent. If it is truly annoying it might be as bad as it got for me 15 years ago, and you should see a doctor because when it was truly stuck in my throat it got worse before it got better.

Hope this helps others.

I was on Minocycline (a cousin to Doxycycline Hyclate) for years. I’m not sure how long exactly as I didn’t write down the date that I started, but I believe I have been on it around 3-4+ years. Well I went to a dermatologist and he instantly looked at the outer area of my arms (just above the elbow) and recognized I am suffering from skin discoloration, and prescribed Doxycycline, and told me to stop taking Minocycline right away. I also have this blue-gray skin discoloration on my back near my shoulder blades. I took my Minocycline for the next two weeks till the Doxycycline came in then stopped the minocycline, and started Doxycycline on Sunday. I take a 100mg pill twice daily with a meal, and thus far have had no issues. Keep in mind that I have been on Minocycline for the past 4 years or so and maybe I’ve been suffering similar side effects on that drug, thus I would be unable to see the difference with Minocycline’s cousin Doxycycline. I am pretty sure the first year or two that I was on Minocycline I was depressed (other things in life may have contributed to this depression, but now that I see all of these people saying they have had mood swings, I must state that I have had many more mood swings in recent years then I ever remember before being on these meds). I have also been extremely sleepy the past few years. I used to NEVER be able to fall asleep in public, but (I believe about the same time I started Minocycline) I gained the ability to sleep anywhere. Now I mean, anywhere. I can sleep even after I get anywhere between 6 and 14 hours of sleep. I have had approx 7-9 hours of sleep on average for the past 6 months, yet am always tired. I can’t remember the last time I haven’t been sleepy, and have had many doctor visits to attempt to discover the reason for this, but hadn’t read the side effects of Minocycline. I’ve still been pretty sleepy since Sunday, but I’ll hope that this Doxycycline isn’t as bad. Anyone else have a similar issue, where you used to be awake, but now you are always sleepy (wake up in the mornings a bit dizzy and confused), and have a hard time concentrating on one thing at a time?

The first few times taking this drug I had extreme nausea even though I had tolerated most previous antibiotics and pills pretty well up to this point.
I thought it was a little odd, but that it would pass.

The nausea finally did pass, but for the past two weeks I have been taking it I've been doing almost nothing but sleeping, and having extreme spells of tiredness.

Gradually every day has just gotten worse and worse than the next while on these pills. I don't want to get out of bed and lately have looked at the clock to see that I've been in bed for twelve hours at a time.

Now, I'm also in very advanced college courses. I initially attributed my sudden inaccuracy and inability to focus on the fact that I was just nervous about the courses, the material, but each day my concentration got worse, and worse and worse. It feels like I have ADD or something, which I've never had.
I felt like I was going insane when I could not even get through a page of material without wanting to jump up and shake myself around (also because of the numbness I got in my legs and arms). Not like me at all.

I have been dizzy, weak, incredibly tired and cold all the time, and entirely unable to focus all since I've started taken these pills. Unlike many of the other people's symtoms posted here, I've experienced severe chills and cold/ numbness in my whole body rather than heat? Except when I go in the sun, which then feels like I'm burning up.

Today was the last straw when I couldn't even get up out of bed, drive normally I was so dizzy, could not normally read one page of material, and the sun felt like it was burning my eyes out.

And reading some of the even worse symptoms others have had, this drug is not worth all the pain and possible permanent damage just to kill a few of these pimples.

bad headache, really bad soreness of throat, tiredness, dizziness, and some itching.

nausea, tiredness, weight gain but gets full easily and am eating less than usual, sunburn, yellowy eyes - my skin looks tired. puffy face. tight throat

Dizzy, nausea, hot flashes, tiredness...going to Vietnam tomorrow--gotta get the more expensive Malarone prescription quick!!