Doxycycline Hyclate and spironolactone

I have been taking 100mg Doxy twice a day for a week now. I'm really glad I found this site because I have been exhausted and I couldn't figure out why. I now know it must be the Doxy. I am taking it for an acne infection. I had been on birth control pills plus spironolactone for over two years- the combination of those two things had totally cleared my skin- so I foolishly decided to go off the birth control and spironolactone thinking my skin would be fine... well two months later my face started breaking out and by the third month I had severe cystic acne on my previously flawless skin! SO the dermatologist put me back on birth control pills and spironolactone, but since that would take at least a month to start working, he also prescribed the Doxy to clear up the infection faster. (I'm providing all of these details in case anyone else is taking Doxy for acne) so I started the Doxy and I think it was by the 4th day or so that I started feeling really tired. I've taken a nap every day for the past few days, AND slept all night. I was going to the gym daily but I could only do half my time on the treadmill last time I went and I haven't gone in two days. I'm also depressed- two days ago I cried three times that one day, yesterday I cried once. I'm just feeling sorry for myself etc- depression for no reason whatsoever. I had been feeling really good about myself all last month- going to the gym, feeling happy & high form the exercise endorphins, finally losing weight, etc, so I know there is NO reason for this tiredness and depression now other than the doxy. Just thought I'd share this because reading all of these posts has really helped me to see that it is just the drug. I will try very hard to force myself to go the gym, even if I can only do half as much. Also, my skin is SLOWLY getting better, but still have another week to go I think. The dermatologist said to take doxy for a month, but I will plan to stop as soon as my skin is clear- hopefully just one more week or two at the most. When my skin is clear I'll take it for one or two more days just to make sure the infection gets totally knocked out, but then that's it, so hopefully I can take it at least one week less than prescribed.

About feeling sick and the sore throat/ "stuck in throat" feeling- I cant stress enough to take it with lots of water and food, standing up, and don't lie down! First of all about feeling sick- I thought I was going to throw up for HOURS one time when I didn't take it with food- horrible feeling!! But this is even worse- about 15 years ago I took doxy and had to go to the hospital because I couldn't breathe, couldn't swallow, and had a splitting migraine headache etc... it had gotten stuck in my esophagus and took days for the symptoms to subside. It took the doctors forever to figure out it was the doxy. You would think I'd never take it again after that, but I know the throat symptom happened from taking it with very little water right before I lay down to go to bed, because I remembered doing that- and I woke up the next day with all of those problems. I still get a little bit of a feeling that I can't swallow as well as I normally can, but it's not that bad- sort of like when you are trying not to cry and feeling "choked up" or with "a lump in your throat"- that kind of a feeling. I think others have described this too, and it's unfortunately normal, to an extent. If it is truly annoying it might be as bad as it got for me 15 years ago, and you should see a doctor because when it was truly stuck in my throat it got worse before it got better.

Hope this helps others.