June 26th
2008
11:22 AM
Possible ovarian cancer triggered by Yasmin.
You need to know this:
The present study suggests that circulating androgens and SHBG levels are *not* strongly associated with ovarian cancer risk,
although levels of fT may be associated with an increased risk among women diagnosed at relatively young age.
Cancer Epidemiol Biomarkers Prev. 2007 Jan;16(1):23-9
Free testosterone (fT)
Increased levels of estrogen stimulate ***increased levels of testosterone***and androgen (increased body hair).
Unlike all the other BC pills...
"Yasmin birth control pill is different than other traditional combined oral contraceptives.
Though it is combined of estrogen (ethinyl estradiol) and progestin (drsp), which has the unique properties than other progestin based pills available in the market. In other combined pills,
***progesin is derived from testosterone***
whereas in Yasmin with drsp, progestin is derived from spironolactone."
We need progesin to come from testosterone to prevent ovarian cancer. We have to LOWER testosterone.
If you have dry eyes...heads up! And get a pelvic ultrasound. If it shows cysts...while most are benign and common...some are NOT.
-- By marnie | Reply | Private Message me
May 6th
2008
6:52 PM
We have all been saying that our issues regard not being informed about all of the possible side effects. And, we know that Singulair works well for some people. Nobody wants to take a good drug away from those for which it probably performs miracles. People who have toxic side effects have a right to know up front.
My observations about montelukast's chemical structure are either general or not quite 100% correct or could be quite vague - so forgive me. I do not claim to be good at organic chemistry. But from doing a little work, I have come up with some observations.
1. It would seem to me that montelukast might work quite well for people who have developed mold category related asthma. I observed that chloroquinolin, a component of montelukast, is a good fungicide effective against Aspergillus, Alternaria, Cladosporium, Penicillium and Candida. Dust mites can only digest if helped by aspergillus so they go into the mold category. Molds produce millions of spores so anyone who lives in contact with mold would be chronically sick from their presence. Then people get hypersensitized to that.
I am probably wrong but I could imagine that montelukast is: 1) a ligand that binds to an empty cysLT1 receptor for a period of time 2) 7-chloroquinolin-2-yl which either acts intact or breaks down into a quinoline fungicide so that it kills the chronic mold/fungus infection and 3) a sulphur/methyl anti-inflammatory component that tells the t-cells that they are not needed so they will die. Wow, that would be great for mold asthma if it was completely non-toxic. It would be also great under controlled circumstances for many people who are mold-miserable. If I am wrong, I better go out into my garage and start inventing such a drug.
This is my visualization to try to explain the side effects of neurotoxicity. So adverse reactions could be to the quinoline component as an allergic reaction or dose related so that it just built up to a toxic level over time. There are many signs that t-cell populations are significantly reduced by montelukast. The fact that the Italians can do it in the test tube might be that it's a chemical component of montelukast designed to cause the t-cells to die.
Montelukast is a large molecule so Artie says it cannot penetrate the blood brain barrier. That would be an argument if nobody was complaining about neuro-psychiatric side effects. The neuro-psychiatric side effects are identical to quinoline and quinolones. When I read about Lariam, it just sounds like a more extreme version of Singulair side effects. Chloroquinolins were used before they invented Lariam, which is stronger. The malaria Plasmodiums became immune. Hallucinations, anxiety, depression, suicidal thoughts are completely consistent in all of the quinoline/quinolones. If montelukast breaks into sub-molecules then quinolines easily penetrate the blood brain barrier.
I find clinical evidence that montelukast may act as more than more molecule. And, that there is a rational for the existence of the chloroquinolin and evidence that it may be the source of toxicity.
I am glad to risk being called crazy. That is what the internet is for. We can present our ideas and discuss. So, just take this with a grain of salt. If I am close to the truth, this post will find it's proper home.
-- By concernedcitizen | Reply | (12) replies | Private Message me
October 13th
2007
10:24 AM
I am now a little nervous after ready all these posts about the bad side effects of Mirena. I had mine inserted yesterday 10/12 but it wasn't for birth control. I have three moderate size fibroids. My doctor said that she has had great results with her other patients on Mirena and it reducing the size of fibroids. I am 34 with two kids and am not looking to have any more but I cannot stand the horrible periods and pain that come with them. The insertion process did hurt some. I did not take any pain killers prior to the appointment. I didn't know not to. I still feel a little bit bloated with mild cramping but nothing serious. I notice that this post revolves mostly as Mirena for birth control. Has any has or had a Mirena for fibroids?
-- By jayferellis | Reply | (2) replies | Private Message me
September 19th
2008
2:02 PM
I had mine inserted the first week of July. Yes, it was freaking uncomfortable getting it done and I had cramping the rest of the day, but my OB warned me of that and I made the decision to go ahead. I'm not in a position to complain about it now.
I bled/spot for 2-3 weeks after insertion. Only heavy enough to require a tampon for the first week, but I had it inserted when I was supposed to be starting my period anyway. Again my OB suggested this and warned me about the possibility of bleeding for up to 6 months. Again my decision to go forward!
Since then I have had cramping once a month like I'm going to start my period and never do. Within the last few weeks I've started getting the acne and an oily scalp. It's all over my back and not poppable. I'm hoping it will eventually subside when my body gets used to the new hormone level I'm giving it. If you think about it, it's the same thing in puberty (ie change in hormones) that kicks off the acne so it doesn't surprise me that this is a side effect. If it doesn't subside I'll make a decision then whether or not to have it out.
I have not had any of the other side effects. In fact I had terrible headaches and neck pain before I got this and those have gotten much better.
I was on the pill for 15 years before getting mirena and I had much worse side effects with that (extreme moodiness, loss of sexual desire, bad cramps, long periods, etc). I tried multiple brands of pills and never found one I was 100% happy with. But I dealt with it because I made the decision to go on B/C.
I'll take the acne over those any day! (not to mention I got pregnant on the pill!!!)
I understand that these side effects suck, but you act like it's the company's fault. They specifically list the common side effects and the majority of the ones you're complaining about are listed in plain site Taken directly from their website:
Menstrual changes
Lower abdominal pain (cramps)
Acne or other skin problems
Back pain
Breast tenderness
Headache
Mood changes
Nausea
Ovarian cysts have been diagnosed in about 12% of Mirena® users. In most cases, the enlarged follicles disappeared spontaneously during two to three months of observation.
Did you think that's just for show? Did you ever stop to consider (before getting the product) you might actually get those side effects and what you would do if you did? It is your body... YOU are the only one responsible for what goes inside it. No one held you down and forced you to do this. Mirena didn't hide anything from you or trick you into it. Take some responsibility for your actions! Quit blaming others. This is a great example of what is wrong with our society today!
Take responsibility! Do your research! Make your own decisions and deal with the consequences of them without blaming others!
If you look at the mirena website it gives you the FDA number to call to report side effects. If you're having major ones call the FDA and report it so that more than just people that stumble upon this forum know about it!
-- By trsturself | Reply | (3) replies | Private Message me