Sulfamethoxazole-Trimethoprim DS Information

What's inside Sulfamethoxazole-Trimethoprim DS

Recent Sulfamethoxazole-Trimethoprim DS Side Effects

Posted by kimgibson 24 days ago
I was prescribed sulfamethoxazole-TMP as a second round of antibiotics to kill off a persistent sinus infection. For the fir...

Posted by queenkathy 2 months ago
I was given this med. and within a few hours the Uti was better but I felt like I had the flu, disoriented, increased appetit...

Posted by dpo1 3 months ago
I had a seizure! This drug caused it. Scary stuff.....I was given this medicine for a spider bite in the emergency room.

Sulfamethoxazole-Trimethoprim DS Chemical Information

sulfamethoxazole - A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfamethoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.

trimethoprim - A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04)