SMZ-TMP DS Information

What's inside SMZ-TMP DS

Recent SMZ-TMP DS Side Effects

Posted by dmz 8 days ago
On Dec 21 2008 my 17 years old was prescribed SMZ/TMP DS 800-160 Tab for possible staph infection. She is/was to take 2 table...

Posted by posrip about 1 month ago
my 95 yr. old mother was given 2 SMZ/TMP pills 12 hrs apart and within hours after the 2nd one, spiked a fever and became flu...

Posted by sexysneez1 about 1 month ago
i have been taking this medication and ive been itching . nearly scratching my arms off and making me throw up . and get ...

SMZ-TMP DS Chemical Information

sulfamethoxazole - A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfamethoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.

trimethoprim - A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04)