Septra DS Information

What's inside Septra DS

Recent Septra DS Side Effects

Posted by laurat 4 months ago
I too was given a generic brand of Septra for an infected insect sting. I experienced a noticeable loss in appetite for the ...

Posted by coral 6 months ago
I am taking Septra for a sinus infection. I am consistently, ridiculously nauseous all day and all night since within two hou...

Posted by edr223 about 1 year ago
My doctor prescribed this (actually the generic version - sulfameth/trimethoprim) medication to me to treat a bite that got i...

Septra DS Chemical Information

sulfamethoxazole - A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfamethoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.

trimethoprim - A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04)